PUBLICATIONS

• Endogenous Linear Plasmids lp28-4 and lp25 Are Required for Infectivity and Restriction Protection in the Lyme Disease Spirochete Borrelia mayonii.

Casselli T, Tourand Y, Gura K, Stevenson B, Zückert WR, Brissette CA.

Infect Immun. 2023 Mar 15;91(3):e0006123. doi: 10.1128/iai.00061-23. Epub 2023 Feb 28. PMID: 36853005.

• Effects of outer surface lipoproteins on the nanomechanical properties of Lyme borrelia.

Munoz C, Ozdogan M, Tourand Y, Casselli T, Brissette CA and Oncel N.

Phys. D: Appl. Phys. 2024. doi:10.1088/1361-6463/ad1350. 

• Borrelia burgdorferi, the Lyme disease spirochete, possesses genetically-encoded responses to doxycycline, but not to amoxicillin.

Saylor TC, Casselli T, Lethbridge KG, Moore JP, Owens KM, Brissette CA, Zückert WR, Stevenson B.

PLoS One. 2022 Sep 30;17(9):e0274125. doi: 10.1371/journal.pone.0274125. eCollection 2022. PMID: 36178885. 

• A murine model of Lyme disease demonstrates that Borrelia burgdorferi colonizes the dura mater and induces inflammation in the central nervous system.

Casselli T, Divan A, Vomhof-DeKrey EE, Tourand Y, Pecoraro HL, Brissette CA.

PLoS Pathog. 2021 Feb 1;17(2):e1009256. doi: 10.1371/journal.ppat.1009256. eCollection 2021 Feb. PMID: 33524035. 

• A small intergenic region of lp17 is required for evasion of adaptive immunity and induction of pathology by the Lyme disease spirochete.

Casselli T, Crowley MA, Highland MA, Tourand Y, Bankhead T.

Cell Microbiol. 2019 Jul;21(7):e13029. doi: 10.1111/cmi.13029. Epub 2019 Apr 16. PMID: 30945408.

• DNA Methylation by Restriction Modification Systems Affects the Global Transcriptome Profile in Borrelia burgdorferi.

Casselli T, Tourand Y, Scheidegger A, Arnold WK, Proulx A, Stevenson B, Brissette CA.

J Bacteriol. 2018 Nov 26;200(24):e00395-18. doi: 10.1128/JB.00395-18. Print 2018 Dec 15. PMID: 30249703.

• Borrelia burgdorferi adhere to blood vessels in the dura mater and are associated with increased meningeal T cells during murine disseminated borreliosis.

Divan A, Casselli T, Narayanan SA, Mukherjee S, Zawieja DC, Watt JA, Brissette CA, Newell-Rogers MK.

PLoS One. 2018 May 3;13(5):e0196893. doi: 10.1371/journal.pone.0196893. eCollection 2018. PMID: 29723263.

• MicroRNA and mRNA Transcriptome Profiling in Primary Human Astrocytes Infected with Borrelia burgdorferi.

Casselli T, Qureshi H, Peterson E, Perley D, Blake E, Jokinen B, Abbas A, Nechaev S, Watt JA, Dhasarathy A, Brissette CA.

PLoS One. 2017 Jan 30;12(1):e0170961. doi: 10.1371/journal.pone.0170961. eCollection 2017. PMID: 28135303.

• Evaluation of the Importance of VlsE Antigenic Variation for the Enzootic Cycle of Borrelia burgdorferi.

Rogovskyy AS, Casselli T, Tourand Y, Jones CR, Owen JP, Mason KL, Scoles GA, Bankhead T.

PLoS One. 2015 Apr 20;10(4):e0124268. doi: 10.1371/journal.pone.0124268. eCollection 2015. PMID: 25893989.

• Use of in vivo Expression Technology for the Identification of Putative Host Adaptation Factors of the Lyme Disease Spirochete.

Casselli T, Bankhead T.

J Mol Microbiol Biotechnol. 2015;25(5):349-61. doi: 10.1159/000439305. Epub 2015 Oct 22. PMID: 26488479.

• Altered murine tissue colonization by Borrelia burgdorferi following targeted deletion of linear plasmid 17-carried genes.

Casselli T, Tourand Y, Bankhead T.

Infect Immun. 2012 May;80(5):1773-82. doi: 10.1128/IAI.05984-11. Epub 2012 Feb 21. PMID: 22354033.

• Vibrio parahaemolyticus inhibition of Rho family GTPase activation requires a functional chromosome I type III secretion system.

Casselli T, Lynch T, Southward CM, Jones BW, DeVinney R.

Infect Immun. 2008 May;76(5):2202-11. doi: 10.1128/IAI.01704-07. Epub 2008 Mar 17. PMID: 18347050.